Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm
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چکیده
منابع مشابه
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
Sox2 is expressed in developing foregut endoderm, with highest levels in the future esophagus and anterior stomach. By contrast, Nkx2.1 (Titf1) is expressed ventrally, in the future trachea. In humans, heterozygosity for SOX2 is associated with anopthalmia-esophageal-genital syndrome (OMIM 600992), a condition including esophageal atresia (EA) and tracheoesophageal fistula (TEF), in which the t...
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ژورنال
عنوان ژورنال: Development
سال: 2007
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.003855